Artichoke extract is used throughout Europe to support liver and gallbladder function and relieve occasional indigestion. It works partly by increasing bile production, which may support increased fat metabolism.
Artichoke (Cynara scolymus) is one of the oldest cultivated plants in the world. It is a grand perennial and has a purplish flower head. The artichoke is native to southern Europe, northern Africa, and the Canary Islands. The flesh of the spike-tipped petals, called "bracts," and the heart of the flower head are eaten as a delicacy.
Artichoke extract is made from the long, deeply serrated basal leaves of the artichoke plant. The reason it is extracted from that part is because the biologically active compounds are greater here than in other parts of the plant. Flavonoids and caffeolyquinic acids are the most active of these compounds. These substances belong to the polyphenol group and include chlorogenic acid, caffeoylquinic acid derivatives (cynarin is one of them), luteolin, scolymoside and cynaroside.
In 1934 cynarin was the first constituent of the extract to be isolated. It is only found in trace amounts from fresh leaves, but is formed by natural chemical changes during the process of drying and extraction of the plant material. At one time it was believed to be the only active component of the extract. Today the whole complex of compounds is considered important.
The chlorogenic acid has recently become known as a powerful antioxidant with some very intriguing and potential applications.
Most modern research has been done with a German extract that is standardized to contain 3% caffeoylquinic acids. A new, more potent extract, is now available on the American market. It is standardized at 15% caffeoylquinic acids that are calculated as chlorogenic acid.
Scientific Studies
In traditional European medicine, the leaves of the artichoke were used as a diuretic to stimulate the kidneys and as a "choleretic" to stimulate the flow of bile from the liver and gall bladder. Bile is a yellowish-brown fluid produced by the liver and stored in the gall bladder. Many of the substances in the bile play a significant role in digestion. In the first half of the twentieth century, French scientists did research that suggested the plant does actually stimulate the kidney and gall bladder.
By mid-century, Italian scientists had isolated a compound from the leaves called cynarin. From the 1950's to the 1980's, synthetic cynarin was used to stimulate the liver and gall bladder and maintain healthy cholesterol. Due to the fact that newer pharmaceuticals have been discovered, cynarin is being used less and less.
Artichoke extract has been proven to be a safe and natural way to maintain and improve your health, because of the many applications it can be used for. It can be safely used as a nutritional supplement and antioxidant with conventional therapies.
Planetary Formulas ARTICHOKE EXTRACT is standardized to 5% cynarin and 15% chlorogenic acids for assured potency of these important compounds.