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Home Jarrow Formulations "Pantethine
Home B Vitamins Health Vitamins Minerals Peak Nutrition "Pantethine
Jarrow Formulations
Jarrow Pantethine, 60 gels
Jarrow Pantethine, 60 gels
Jarrow Pantethine, 60 gels
Avg. Rating:
Retail price: $29.95
Our price: $14.55
You save: $15.40
51.42 % off
Quantity:
Availability:
Item Number : JR-063
Package Description : 60 Gels
Product Weight Per Unit : 0.4
Serving Size : 1 Capsule
Number of Servings : 60
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Jarrow Pantethine, 60 gels

Jarrow Formula Pantethine is a derivative of vitamin B5 and the stable disulfate form of pantetheine, which is the active component of Coenzyme A (CoA). Pantethine supports lipid metabolism by its ability to raise levels of CoA, a cofactor involved in several metabolic pathways including carbohydrate and lipid metabolism. CoA combines with acetyl groups to form Acetyl CoA, a participant in energy production.

Pantethine occurs as a colorless or light yellow viscous substance. It is soluble in water and alcohol, and practically insoluble in ether, chloroform, acetone, benzene. The aqueous solution is neutral, and has a bitter taste.

Pantethine has been found to decrease serum levels of

  • Total Cholesterol
  • Low-density lipoprotein cholesterol (LDL-C)
  • Apolipoprotein B
  • Triglycerides

It has also been found to increase high-density lipoprotein cholesterol (HDL-C) and apolipoprotein A1 levels. The mechanism of the possible lipid-modulating activity of pantethine is not understood. In isolated hepatocytes, pantethine has been shown to inhibit both cholesterol and fatty acid synthesis. It is speculated that pantethine, by acting as a precursor of coenzyme A, may enhance the beta-oxidation of fatty acids. However, this has not been confirmed.

Another hypothesis is that the lipid-modulating effect of pantethine may be mediated via its metabolite cysteamine. It is argued that there is little pantethine found in the serum following its ingestion and that most of a dose is metabolized to pantothenic acid and cysteamine. Since pantothenic acid does not possess lipid-modulatory activity, cysteamine might. This lipid-modulatory activity could occur via the inhibition of acetyl coenzyme A carboxylase activity and the stimulation of hepatic fatty acid oxidation, resulting in lowered triglyceride levels, and via the inhibition of HMG-CoA reductase activity, resulting in lowered cholesterol levels. Again, this has not been confirmed. Further, cysteamine, a treatment for cystinosis, has not been found to have lipid-lowering activity in those with this rare genetic disorder. Nor, does pantethine appear to be efficacious in the treatment of cystinosis.

Nutritional Facts

Each Serving Size (caps) 1 provides:
Ingredients Amount per 1 serving % Daily Value
Pantethine      450 mg *

Ingredient Details :
Pantethine 450 mg

Suggested Use :
Take 1 to 3 softgels per day with meals, or as directed by your qualified health consultant.

Warnings :

Softgel consists of gelatin, glycerin, and water. Natural annatto and carob are included as a light barrier. No wheat, no gluten, no soy, no dairy, no egg, no fish/shellfish, no nuts/tree nuts. Keep out of the reach of children. These statements have not been approved by the Food and Drug Administration (FDA). This product is not intended to cure, treat, diagnose or prevent any disease.

   Product Faqs :
 
What are the benefits of Vitamins and Minerals?
Vitamins are essential to sustain life and we must get them from our natural foods or dietary supplements. The nutrition they provide help people feel better, more energetic and assist the body with normal functions. Vitamins and minerals are necessary for our growth, vitality and well-being.

Vitamins and minerals are essential for our body but they are no replacement for food. A vitamin or mineral has no caloric or energy value by itself, but when taken as a dietary supplement to your daily food intake, they can help supplement your daily diet by balancing out the deficiencies of improper eating habits, overcooked foods and non-nutritive, processed foods. Sometimes vitamins are used as therapies for various ailments and disease.
What role do minerals play to keep us healthy?
In addition to vitamins, your body needs minerals to aid in the assimilation of the vitamins. Minerals help accelerate the billions of chemical reactions occurring in your body all the time. Some help in the efficient metabolization of proteins, fat and carbohydrates. Others help regulate the utilization of certain vitamins. Minerals actually become components of the body structure - bones, cartilage, toenails and fingernails, and they contribute toward hardness and strength.
I have heard that taking Vitamin E increases DHEA levels in body, is that true?

Vitamin E has recently been shown to protect/ preserve critical DHEA levels in the brain. It is suspected that preserving DHEA levels in the brain may delay the onset of many mental degenerative diseases associated with "getting older". According to a study done by Japanese researchers, vitamin E deficient diet notably reduced brain (adrenal) DHEA levels. However, using more vitamin E did not increase adrenal DHEA levels beyond normal values.

When can magnesium deficiency occur?

Even though dietary surveys suggest that many Americans do not consume magnesium in recommended amounts, magnesium deficiency is rarely seen in the United States in adults. When magnesium deficiency does occur, it is usually due to excessive loss of magnesium in urine, gastrointestinal system disorders that cause a loss of magnesium or limit magnesium absorption, or a chronically low intake of magnesium.

Who may need extra magnesium?
Magnesium supplementation is usually indicated when a specific health problem or condition causes an excessive loss of magnesium or limits magnesium absorption. Healthy adults who eat a varied diet do not generally need to take a magnesium supplement.
Why is Magnesium important?
Magnesium aids in the transport of oxygen to muscle tissue, which promotes strength, endurance and relaxation. Magnesium also activates enzymes necessary for the metabolism of carbohydrates and amino acids.
What are the essential nutrients for our health?
It's important to remember that there are six nutrients essential for energy, proper functioning of the organs, utilization of food and cell growth: carbohydrates, proteins, fats, vitamins, minerals and water. These nutrients are utilized by the body through the digestive process, which simplifies the nutrients via enzymatic actions that break the nutrients down into smaller chemical fragments. These are then absorbed through the walls of the digestive tract and eventually enter the blood stream to be utilized by the body.