Jarrow Formulas L-Carnosine 500 mg - 90 Caps

L-Carnosine- Anti Ageing from the Inside Out
When most of us consider using anti-ageing treatments, we immediately think about using topical skin care products. We can spend £'s on creams offering miraculous cures, only to find the effects are minimal or temporary at best. Good skin starts from the inside and literally grows outwards and although we can certainly make a difference by using creams we can't ignor the possibilities of what can be done from the inside out. Informed scientists have always looked at ways in which the ageing process can be affected from the inside, examining the elements which contribute towards the ageing process and seeking a solution based on real science and not on cosmetic promises. From the Inside
One of the reasons why older people and animals look different than younger ones has to do with changes in the proteins of the body. Proteins are the substances responsible for the daily functioning of living organisms, which gives protein deterioration its dramatic impact on the body's function and appearance. Many lines of research over the last decade have converged on protein modification as a major pathway for aging and degenerative diseases. These modifications result from oxidation (by free radicals) and interrelated processes such as protein-sugar reactions (glycation). L-Carnosine - "The Super Peptide"
L-Carnosine (kahr´no-sën), is a well-known neuropeptide consisting of alanine and histidine (beta-alanyl-L-histidine). It is normally made in the human body and is found at high levels in brain, innervated tissues, the lens of the eye, and skeletal muscle tissue. In laboratory studies, it has been demonstrated that carnosine has the ability to protect cells against oxidative stress as well as to increase their resistance toward functional exhaustion and accumulation of senile features. Mechanisms of such protection are explained in terms of:

• Proton buffering (maintaining pH balance in the muscles in heavy exercise)
• Heavy metal chelating (especially copper and zinc)
• Free-radical and active sugar molecule scavenging (prevents glycation and carbonylation of proteins)
• Preventing the modification of biomacromolecules thereby keeping their native functionality under oxidative stress

Physiological concentrations (20-30 micromoles, or mM) in standard media prolong the in-vitro life span of human fibroblast cells and strongly reduce the normal features of senescence (ageing). In laboratory animals, carnosine clearly improved the external appearance of experimental animals and produced apparent beneficial effects on behavioral parameters and average life span.

• Age-related conditions that carnosine may be useful for include:
• neurological degeneration (Alzheimer´s, Parkinson´s, epilepsy depression, schizophrenia, mild cognitive impairment, dementia and stroke)
• Autistic Spectrum Disorders, Asperger´s syndrome, ADHD, dyslexia
• cellular senescence (ageing) in general
• cross-linking of the eye lens (cataracts)
• cross-linking of skin collagen (skin ageing)
• formation of advanced glycation end products (AGES)
• accumulation of damaged proteins
• muscle atrophy
• brain circulation deficit (stroke)
• cardiovascular conditions
• diabetes and its complications.

L-Carnosine is a dipeptide composed of the covalently bonded amino acids alanine and histidine and is found in the:

• Brain
• Heart
• Skin
• Muscles
• Kidneys
• Stomach

L-Carnosine is naturally produced in the body by the enzyme carnosine synthetase. L-Carnosine supports healthy aging and cellular rejuvenation by its effects on two mechanisms: glycosylation and FREE RADICAL DAMAGE. Glycosylation is the oxidation of protiens by glucose resulting in cross-linking of proteins and which is implicated in loss of cell function, genome integrity and accelerated aging. L-Carnosine also protects the aging process of the brain by retarding lipid peroxidation and stabalizing cell membranes.

Ingredient Details:Cellulose, rice powder and magnesium sterate

Suggested Use:Take 1 to 3 capsules per day, with juice or water on an empty stomach, or as directed by your qualified health consultant.

Cautions:Capsule consists of gelatin.

About: Jarrow Formulas is based in Los Angeles California USA and is a formulator and supplier of extra ordinary nutritional supplements. Founded in 1977 and incorporated in 1988 today Jarrow Formulas markets its products in the United States Mexico Canada and throughout the world. Jarrow Formulas'' mission is reflected in its motto ''Superior Nutrition and Formulation".

Jarrow Formulas'' entire line of nutritional products includes vitamins minerals probiotics standardized herbal concentrates amino acids enzymes and enteral nutrition products.