Relora® is an amazing new natural stress relief and anti-anxiety element used to control stress related eating and drinking. Relora® also has the benefit of being non-sedating with potential anti-depressant properties; it may also help in weight loss. Relora works by binding to stress receptors in the nervous system to endorse relaxation and feelings of well being while ignoring receptors connected with sedation. Relora™ is a patented, proprietary blend of two plant extracts magnolia officinalis and phellodenron amurense.

Relora®:

• Provides stress relief
• Controls stress eating and related drinking behavious
• Helps in weight loss (when weight is caused by stress)
• Provides feeling of relaxatin
• May provide more restful sleep
• Is gentle on stomach

Relora® and Weight Loss: Did you know that over twenty percent (20%) of American adults are obese with a stress-related condition known as "metabolic syndrome? Chronic stress can cause cravings for high-fat, high-carbohydrate foods. The stress eating for these foods leads to dangerous weight gain, primarily around the waist. Dr. Elissa Epel and colleagues at the University of California, San Francisco have now clearly shown that persons who are high reactors to the stress hormone called cortisol, intake more calories and more sweet foods under stress. Their recent study also showed that greater food consumption took place in high cortisol reactors when they were in a negative mood.

Over twenty percent (20%) of adults have an obesity-like condition distinguished by too much amount of abdominal fat. This condition is associated with stress-induced hormone imbalances, especially imbalances of cortisol and DHEA. Relora® can stabilize cortisol and DHEA levels in stressed individuals, stimulate relaxation, and act as an aid to weight loss and stress eating or drinking.

Relora®, a natural dietary supplement prepared by Next Pharmaceuticals, Inc. in Irvine California, was developed to enhance mood, help stressed individuals relax and standardize the hormones related to stress eating. Preface findings propose that Relora® can reduce the cravings for high fat, high sugar foods in stressed individuals, most likely due to its ability to regularize stress hormone levels that cause these cravings. Thus helping in weight loss.

Relora® is Non-Sedative but Provides Relaxation: In central nervous system receptor binding examines, the plant extracts in Relora® bind to several important targets linked with anxiety. It does not tie to the benzodiazepine receptors that would cause sedation, yet has the relaxing qualities of the benzodiazepine class of drugs in a validated anxiolytic animal model. In addition, it regulates hormone levels allied with stress-induced obesity and stress eating/drinking behavior. Hence, providing relaxation in addition to aid in weight loss.

Stress has been shown to play a significant role in a wide variety of conditions and disease states. Recent work from the National Institute of Health (NIH) and other major research centers has demonstrated that stress is a significant contributor to immune dysfunction, cardiovascular disease, other age-related disorders, and to excess body fat.

Human Trials/ Studies: The first formulation of Relora® was tested and found to be a safe, efficient, fast acting, non-sedating dietary supplement that helps control occasional mild anxiety. Fifty (50) subjects were treated with Relora® for two weeks. The recommended dosage was 200 mg of Relora® three times daily. (The new and improved Relora dosage is 250 mg three times daily.) Based on pre-clinical studies, Relora® was designed and evaluated against the following concepts: Relora® helps control occasional mild anxiety or mild depression and the associated symptoms including irritability, emotional ups and downs, restlessness, tense muscles, poor sleep and concentration difficulties.

• Post-trial analysis revealed an excellent agreement(82%) with the pretrial concept
• Relaxation was reported by 78% of the patients
• Though the product does not cause significant sedation, 74% of the patients had a restful sleep
• Relora® was judged to be gentle on the stomach by 94% of the subjects
• No significant side effects were reported
• When subjects were asked about drowsiness, only 24% reported that they were drowsy.

A second trial was started to measure cortisol and DHEA levels in patients with mild to moderate stress. Elevated cortisol levels and depressed DHEA levels are associated with chronic stress. A two-week regimen of Relora® caused:

• Significant (P = 0.003) increase in salivary DHEA (227%) and
• Significant (P = 0.01) decrease in morning salivary cortisol levels (37%).

These noteworthy findings support Relora’s ability to provide stress relief and its potential role in weight loss and stress eating and related drinking behavior.