1Fast400 Idebenone 500mg, 90 caps (90 Caps)

Idebenone is a synthetic analog (variant) of one of life's most essential biochemicals, coenzyme Q10 (Co Q10).  Co Q10 is an important antioxidant component of the lipid (fatty) membranes that surround all cells, as well as the lipid membranes surrounding the various organelles ("little organs"), such as mitochondria and microsomes, inside cells.

Co Q10 is also an important member of the "Electron Transport Chain" within mitochondria, which are the "power plants" of the cell. Most of the oxygen we breathe is used inside the electron transport chain to produce much of the ATP bioenergy that powers virtually every activity of our cells and bodies.

Without CoQ10,Idebenone is a "better Co Q10" that has been extensively researched the past 15 years. When blood flow is seriously reduced to any part of the body, as in a heart attack, stroke, trauma, shock, or chronic poor blood circulation- cellular/ mitochondrial oxygen (O2) levels quickly drop in the affected region.

Because oxygen is seven to eight times more soluble in the lipid zones of cell membrane, compared to the watery compartments of the cell, there is still sufficient oxygen remaining in the membranes of cells and organelles, as well as in the electron transport chain, to auto-oxidize Co Q10.  

As the Co Q10 auto-oxidizes, hydrogen peroxide, superoxide and hydroxl free radicals are rapidly formed in massive numbers. These free radicals quickly damage cell/ organelle structure and function, as well as rapidly halt ATP energy generation by the electron transport chain.

Studies have shown that under the same cellular low oxygen conditions that cause Co Q10 to act as a pro-oxidant producer of damaging free radicals, Idebenone prevents the free radical dam-age and maintains relatively normal cell ATP levels.

While Idebenone can effectively substitute for Co Q10's positive and life essential functions, it doesn't have Co Q10's free radical producing and energy crashing "dark side" which occurs under hypoxic (low oxygen) conditions.

Idebenone's potential benefits fall into five categories; antiaging, energy enhancement, cognition enhancement, organ protector and protector against excitatory amino acid neurotoxicity.

Idebenone will work even better than Co Q10 within the electron transport chain to keep energy production high, even under hypoxic conditions. This is especially critical to brain and heart cells that may be rapidly damaged during low ATP production episodes that occur due to poor tissue oxygenation.

Studies have shown that Idebenone can divert 10% of cellular oxygen away from toxic iron induced free radical generation, to beneficial ATP energy production under hypoxic conditions.Mild cellular hypoxia can occur even from intense exercise, or even from mild exercise done by out of shape "couch potatoes."

Human and animal studies have demonstrated that Idebenone can enhance serotonin production that enhances brain structure and function even under far less than optimal conditions,e.g. with a very low tryptophan diet, or in patients with cerebrovascular dementia. Idebenone has enhanced cholinergic nerve function and consequent learning ability even under hypoxic conditions, or when an anti-cholinergic drug (Scopolamine) was administered.

Idebenone has increased cellular catecholamine (dopamine, adrenalin and noradrenanlin) production by enhancing cellular uptake of the precursor amino-acid tyrosine. Idebenone enhances long term potentiation in hippocampal nerve cells, a key part of memory formation and consolidation.

Idebenone has restored glucose (brain fuel) utilization and ATP production in ischemic (poor blood flow) rat-brain.Idebenone has been shown to enhance general cerebral metabolism, lessen the damage from strokes, and has been used to treat Alzheimer's and other dementias.

And like the original nootropic drug piracetam, Idebenone has been shown to promote information transfer across the corpus callosum, the membrane separating the right and left brain hemispheres.This is turn may promote the union/ integration of the logical (yang) and intuitive (yin) halves of the brain/ mind.

Idebenone protects organs in many ways, it cushions them against hypoxic (low oxygen) and/ or ischemic (poor blood flow) damage. Idebenone enhances both normal and hypoxic ATP energy generation.

Idebenone is a powerful antioxidant, more so than Co Q10, and in some studies is 30 to 100 times more effective, than vitamin E or vinpocetine as a free radical quencher within the brain cells. Idebenone lessens the free radical induced mtDNA damage that accumulates acceleratingly over a lifetime, slowing organ damage and aging.

With all these powers, Idebenone should now rightfully take its place in the first rank of anti-aging,nootropic,energizer drugs, along with Hydergine, piracetam, vinpocetine, deprenyl and GH3/KH3.

Because of its synergy with other life extension drugs, those also taking any or all of Hydergine, piracetam (and its analogues), vinpocetine, deprenyl, GH3/ KH3 may benefit from even just one 45mg tablet a day, especially if taken regularly on a long-term basis.  Because idebenone is fat soluble, it is best taken with a fat rich meal, or with lipid absorption enhancing agents such as lecithin or phosphatidyl choline.

Numerous studies have shown that idebenone is well distributed through-out the body after absorption, accumulating in cellular and organelle membranes, as well as in the electron transport chain, exactly where it does the most good!

Expert Advice:Idebenone is said to promote nerve growth factors in the brain. It appears to reduce tinnitus (ringing in the ears) and shown in topical applications to treat wrinkles.

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